Publications


2023

Kostyushev D., Brezgin S., Kostyusheva A., Ponomareva N., Zakirova N.F., Egorshina A., Yanvarev D., Bayurova E., Kondrashova A., Goptar I., Nikiforova A., Sudina A., Babin Y., Gordeychuk I., Lukashev A., Chulanov V., Ivanov A., Zakirova N., Zamyatnin A.A. Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus. Molecular Therapy: Nucleic Acids, 2023, published online.

Smirnova O.A.*, Ivanova O.N.*, Mukhtarov F., Valuev-Elliston V.T., Fedulov A.P., Rubtsov P.M., Zakirova N.F., Kochetkov S.N., Bartosch B., Ivanov A.V. Hepatitis delta virus antigens trigger oxidative stress, activate antioxidant Nrf2/ARE pathway, and induce unfolded protein response. Antioxidants, 2023, 12(4), 974.

Golikov M.V., Bartosch B., Smirnova O.A., Ivanova O.N., Ivanov A.V. Plasma-Like Culture Medium for the Study of Viruses. mBio. 2023, 14(1), e02035-22.

Smirnova O.A., Ivanova O.N., Fedyakina I.T., Yusubalieva G.M., Baklaushev V.P., Yanvarev D.V., Kechko O.I., Mitkevich V.A., Valuev-Elliston V.T., Vorobiev P.O., Fedorov F.S., Bartosch B., Lipatova A.V., Ivanov A.V. SARS-CoV-2 establishes a productive infection in hepatoma and glioblastoma multiforme cell lines. Cancers, 2023, 15, 632.

Kostyushev D., Kostyusheva A., Brezgin S., Ponomareva N., Zakirova N.F., Egorshina A., Yanvarev D., Bayurova E., Sudina A., Goptar I., Nikiforova A., Dunaeva E., Lisitsa T., Abramov I., Frolova A., Lukashev A., Gordeychuk I., Zamyatnin A.A., Ivanov A., Chulanov V. Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR/Cas9. Molecular Therapy: Nucleic Acids, 2023, 31, P482-493.

Duponchel S., Monnier L., Molle J., Bendridi N., Alam M.R., Gaballah A., Grigorov B., Ivanov A., Schmiel M., Odenthal M., Ovize M., Rieusset J., Zoulim F., Bartosch B. Hepatitis C virus replication requires integrity of mitochondria-associated ER membranes. JHEP Reports, 2023, 5(3), 100647.

Matyugina E, Petushkov I, Surzhikov S, Kezin V, Maslova A, Ivanova O, Smirnova O, Kirillov I, Fedyakina I, Kulbachinskiy A, Kochetkov S, Khandazhinskaya A. Nucleoside analogs that inhibit SARS-CoV-2 replication by blocking interaction of virus polymerase with RNA. Int. J. Mol. Sci. 2023; 24(4), 3361.

Ivanova O.N., Krasnov G.S., Snezhkina A.V., Kudryavtseva A.V., Fedorov V.S., Zakirova N.F., Golikov M.V., Kochetkov S.N., Bartosch B., Valuev-Elliston V.T., Ivanov A.V. Transcriptome analysis of redox systems and polyamine metabolic pathway in hepatoma and non-tumor hepatocyte-like cells. Biomolecules. 2023, 13(4), 714.

Brezgin S., Kostyusheva A., Ponomareva N., Bayurova E., Kondrashova A., Frolova A., Slatinskaya O., Fatkhutdinova L., Maksimov G., Zyukin M., Gordeychuk I., Lukashev A., Makarov S., Ivanov A., Zamyatin A.A., Chulanov V., Parodi A., Kostyushev D. Hydroxychloroquine enhances cytotoxic properties of extracellular vesicles and extracellular vesicle-mimetic nanovesicles loaded with chemotherapeutics. Pharmaceutics, 2023, 15(2), 534.

2022

Vorobyev, P.O.; Kochetkov, D.V.; Chumakov, P.M.; Zakirova, N.F.; Zotova-Nefedorova, S.I.; Vasilenko, K.V.; Alekseeva, O.N.; Kochetkov, S.N.; Bartosch, B.; Lipatova, A.V.; Ivanov, A.V. 2-Deoxyglucose, an Inhibitor of Glycolysis, Enhances the Oncolytic Effect of Coxsackievirus. Cancers 2022, 14, 5611.

Golikov, M.V.; Karpenko, I.L.; Lipatova, A.V.; Ivanova, O.N.; Fedyakina, I.T.; Larichev, V.F.; Zakirova, N.F.; Leonova, O.G.; Popenko, V.I.; Bartosch, B.; Kochetkov, S.N.; Smirnova, O.A.; Ivanov, A.V. Cultivation of Cells in a Physiological Plasmax Medium Increases Mitochondrial Respiratory Capacity and Reduces Replication Levels of RNA Viruses. Antioxidants 2022, 11, 97.

Zakirova, N.F., Kondrashova, A.S., Golikov, M.V. Ivanova O.N., Ivanov A.V., Isaguliants M.G., Bayurova E.O. Expression of HIV-1 Reverse Transcriptase in Murine Cancer Cells Increases Mitochondrial Respiration. Molecular Biology. 2022, 56, 723–734.

Kichatova V.S., Asadi Mobarkhan F.A., Potemkin I.A., Zlobin S.P., Perfilieva O.M., Valuev-Elliston V.T., Ivanov A.V., Solonin S.A., Godkov M.A., Belikova M.G., Mikhailov M.I., Kyuregyan K.K. Assessment of Diagnostic Specificity of Anti-SARS-CoV-2 Antibody Tests and Their Application for Monitoring of Seroconversion and Stability of Antiviral Antibody Response in Healthcare Workers in Moscow. Microorganisms. 2022; 10(2):429.

Golikov, M.V., Valuev-Elliston, V.T., Smirnova, O.A., Ivanov A.V. Physiological Media in Studies of Cell Metabolism. Molecular Biology. 2022, 56, 629–637.

Vinogradskaya, G.R., Ivanov, A.V., Kushch, A.A. Mechanisms of Survival of Cytomegalovirus-Infected Tumor Cells. Molecular Biology. 2022, 6, 668–683.

Ivanov A.V., Khomutov A.R. Biogenic Polyamines and Related Metabolites. Biomolecules, 2022, 12(1), 14.

2021

Savvateeva, E.; Filippova, M.; Valuev-Elliston, V.; Nuralieva, N.; Yukina, M.; Troshina, E.; Baklaushev, V.; Ivanov, A.; Gryadunov, D. Microarray-based detection of antibodies against SARS-CoV-2 proteins, common respiratory viruses and type I interferons. Viruses 2021, 13, 2553.

Axfors C, Janiaud P, Schmitt AM et al. Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials. BMC Infect Dis. 2021, 21(1), 1170.

Gorchakov A., Kulemzin S., Guselnikov S., Baranov K., Belovezhets T., Mechetina L., Volkova O., Najakshin A., Chikaev N., Chikaev A., Larichev V., Gulyaeva M., Markhaev A., Kononova Y., Alekseyev A., Shestopalov A., Yusubalieva G., Klypa T., Ivanov A., Valuev-Elliston V., Baklaushev V., Solodkov P., Taranin A. Isolation of a panel of ultra-potent human antibodies neutralizing SARS-CoV-2 and viral variants of concern. Cell Discovery, 2021, 7, 96.

Masalova O.V., Lesnova E.I., Klimova R.R., Ivanov A.V., Kushch A.A. Mesenchymal Stem Cells Can Both Enhance and Inhibit the Cellular Response to DNA Immunization by Genes of Nonstructural Proteins of the Hepatitis C Virus. Int. J. Mol. Sci. 2021, 22(15), 8121. doi: 10.3390/ijms22158121.

Lesnova E.I., Masalova O.V., Permyakova K.Y., Kozlov V.V., Nikolaeva T.N., Pronin A.V., Valuev-Elliston V.T., Ivanov A.V., Kushch A.A. Difluoromethylornithine (DFMO), an Inhibitor of Polyamine Biosynthesis, and Antioxidant N-Acetylcysteine Potentiate Immune Response in Mice to the Recombinant Hepatitis C Virus NS5B Protein. Int. J. Mol. Sci. 2021, 22(13), 6892.

Karpenko I.L., Valuev-Elliston V.T., Ivanova O.N., Smirnova O.A., Ivanov A.V. Peroxiredoxins-The Underrated Actors during Virus-Induced Oxidative Stress. Antioxidants (Basel). 2021, 10(6), 977.

Fedorov VS, Ivanova ON, Karpenko IL, Ivanov AV. The Immune Response to the Novel Coronavirus Infection. Journal of Clinical Practice. 2021, 12(1), 33–40.

2020

Shomuradova A.S., Vagida M.S., Sheetikov S.A., Zornikova K.V., Kiryukhin D., Titov A., Peshkova I.O., Khmelevskaya A., Dianov D.V., Malasheva M., Shmelev A., Serdyuk Y., Bagaev D.V., Pivnyuk A., Shcherbinin, D.S., Maleeva A.V., Shakirova N.T., Pilunov A., Malko D.B., Khamaganova E.G., Biderman, B., Ivanov A.V., Shugay M., and Efimov G.A. SARS-CoV-2 epitopes are recognized by a public and diverse repertoire of human T-cell receptors. Immunity, 2020, 52, 1245-1257.

Mastrodomenico V., Esin J., Qazi S., Khomutov M., Ivanov A.V., Mukhopadhyay S., Mounce B. Virion-associated polyamines transmit with bunyaviruses to maintain infectivity and promote entry. ACS Infect. Dis. 2020, 6(9), 2490–2501.

Baklaushev V.P., Averyanov A.V., Sotnikova A.G., Perkina A.S., Ivanov A.V., Yusubalieva G.M., Novikova O.N., Shikina V.E., Dupik N.V., Kedrova A.G., Sanzharov A.E., Shirshova E.V., Balionis O.I., Valuev-Elliston V.T., Zakirova N.F., Glazov Y.N., Panukhina I.A., Soloviev N.A., Vinokurov A.G., Ivanov Yu.V., Vasilev V.N., Klypa T.V., Troitsky A.V. Safety and efficacy of convalescent plasma for COVID-19: the preliminary results of a clinical trial. Journal of Clinical Practice. 2020, 11(2), 38-50.

Jansons J., Bayurova E., Skrastina D., Kurlanda A, Fridrihsone I, Kostyushev D., Kostyusheva A., Artyuhov A., Dashinimaev E., Avdoshina D., Kondrashova A., Valuev-Elliston V., Latyshev O., Eliseeva O., Petkov S., Abakumov M., Hippe L., Kholodnyuk I., Starodubova E., Gorodnicheva T., Ivanov A., Gordeychuk I., Isaguliants M. Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells. Vaccines, 2020, 8(2), 318.

Masalova O.N., Lesnova E.I., Klimova R.R., Momotyuk E.D., Kozlov V.V., Ivanova A.M., Payushina O.V., Butorina N.N., Zakirova N.F., Narovlyansky A.N., Pronin A.V., Ivanov A.V., Kushch A.A. Genetically Modified Mouse Mesenchymal Stem Cells Expressing Non-Structural Proteins of Hepatitis C Virus Induce Effective Immune Response. Vaccines, 2020, 8(1), 62.

Kukhanova M.K., Karpenko I.L., Ivanov A.V. DEAD‐box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs. Molecules, 2020, 25 (4), 1015.

Khomic O.A., Ivanov A.V, Bartosch B. Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis. Cells, 2020, 9(1), 24.

Isaguliants M.G., Bartosch B., Ivanov A.V. Redox Biology in Infection and Consequent Disease. Oxid. Med. Cell. Longev., 2020, vol. 2020,. Article ID 5829521.

2019

Kukhanova M.K., Tunitskaya V.L., Smirnova O.A., Khomich O.A., Zakirova N.F., Ivanova O.N., Ziganshin R, Bartosch B., Kochetkov S.N., Ivanov A.V. Hepatitis C virus RNA-dependent RNA polymerase is regulated by cysteine S-glutathionylation. Oxid. Med. Cell. Longev., 2019, vol. 2019, Article ID 3196140.

Fedorova N.E., Chernoryzh Y.Y., Vinogradskaya G.R., Emelianova S.S., Zavalyshina L.E., Yurlov K.I., Zakirova N.F., Verbenko V.N., Kochetkov S.N., Kushch A.A., Ivanov AV. Inhibitor of polyamine catabolism MDL72.527 restores the sensitivity to doxorubicin of monocytic leukemia Thp-1 cells infected with human cytomegalovirus. Biochimie, 2019, 158, 82-89.

Jansons J., Sominskaya I., Petrakova N., Starodubova E.S., Smirnova O.A., Alekseeva E., Bruvere R., Eliseeva O., Skrastina D., Kashuba E., Mikhailova M., Kochetkov S.N., Ivanov A.V., Isaguliants M.G. The immunogenicity in mice of HCV core delivered as DNA is modulated by its capacity to induce oxidative stress and oxidative stress response. Cells, 2019, 8(3), 208.

Chernoryzh Ya.Yu., Fedorova N.E., Yurlov K.I., Simonov R.A., Kornev A.B., Karpov D.S., Zakirova N.F., Ivanov A.V., Kushch A.A., Gintsburg A.L. Resistance of THP-1 cells infected with cytomegalovirus to anti-tumor antibiotic doxorubicin and restoration the sensitivity by inhibitors of the molecular way PI3K/AKT/mTOR. Doklady Biochemistry and Biophysics, 2019, 489(4), 433-437.

Bayurova E., Jansons J., Skrastina D., Smirnova O., Mezale D., Kostyusheva A., Kostyushev D., Petkov S., Podschwadt P., Valuev-Elliston V., Sasinovich S., Korolev S., Warholm P., Latanova A., Starodubova E., Tukhvatulin A., Latyshev O., Selimov R., Metalnikov P., Komarov A., Ivanova O., Gorodnicheva T., Kochetkov S., Gottikh M., Strumfa I., Ivanov A., Gordeychuk I., Isaguliants M. HIV-1 reverse transcriptase promotes tumor growth and metastasis formation via ROS-dependent upregulation of Twist. Oxid. Med. Cell. Longev., 2019, vol. 2019, Article ID 6016278.